For your visit one day appears to be sufficient to get acquainted with the city and its sights.
Distances are walkable in all cases, unless you are interested in visiting the European Parliament building which is situated on the outskirts of the city center.
Love its North European architecture woven into Southern fabric.
Worthy attractions: Cathédrale Notre-Dame [did not tour inside].
Left for another visit: Museums at Palais des Rohan; Petite France; Ponts-Couverts; Musée Alsacien; boat excursion around town center.
Last visit: August 2008.

The cosmopolitan capital of Alsace – and one of the European Union capitals – is a good-looking town with a number of attractions within a fairly compact central area.
Things to See
Unfortunately, we only stayed in Strasbourg for an overnight visit, arriving late enough to do little more than have a dinner and leaving early enough next day to not have much time for sightseeing. On a night-time stroll around central squares, we came up to the great Notre-Dame cathedral ♥♥ that earns its marks just because of its exterior – we have no doubt that a third heart will be added once we visit the cathedral interior in the future.
The German influences in the Alsatian culture resulted in a propensity of half-timbered buildings on central streets of Strasbourg – the look that I always find attractive.
A number of museums await our someday return to this city.
Places to Eat
A la tête de lard ♥♥ is a family restaurant on Rue Hannong, frequented by locals, although visitors to town make up a good portion of clientele. Nicely appointed and decorated room, understated but quick service. Excellent tartes flambées and selection of local patés; of the main courses, confit de canard was especially tasty. Our damage: €85 for five appetizers and two entrées, plus half-carafe of house wine and two apéritifs.